Study on Biomarkers for Early Diagnosis of Alzheimer’s Disease
Population-based cohort study tracking biomarker progression in elderly carriers — designed to detect AD years before clinical onset.
Your doctor said "come back when you're 60." But your brain is changing now.
Individually, we're navigating this alone—spending years testing interventions in isolation, unsure if they're working. Together, we're building the infrastructure to compress decades of trial-and-error into months of validated results.
The Phoenix app and community combine accountability, data-driven tracking, Phoenix AI personalization, and collective bargaining power. So you can discover what works faster, validate it with science, and access tomorrow's treatments today.
"Never Optimize Alone"
"I signed up for Phoenix to get access to things like the Neuronic helmet. But what I found — maybe more importantly — is a group that understands where I’m coming from."
Watch John’s story →
565 members in private forum sharing protocols, biomarker results, and real-world insights. Find answers from people 6 months ahead of you on the same journey.
Phoenix AI-matched peer groups for consistent action
Access to leading researchers and doctors
"Upload your health data. See exactly what's working. Get your next step in 30 seconds."
"The Phoenix app is building something personal that works for me, not just a one-size-fits-all protocol. Because what works for one person does not work for another."
Watch Donna’s story →
All your health data in your pocket — finally
Discover what moves the needle for YOUR unique biology
Learn from members with similar genetics and health profiles
"Validate what actually works on you, not on averages."
"I really like that about Phoenix — all these facts are getting amassed, and if there is a trend, we can see it. That’s really great. It’s not just n=1 anymore."
Watch Gertrude’s story →
Track supplements with community insights
Upload blood tests and get APOE4-specific insights
Magnesium glycinate 400 mg + L-theanine 200 mg, 30 min before bed.
So far (vs. baseline)
Sleep latency
−8 min
HRV (overnight)
+12%
Phoenix AI proposes interventions tied to your goals, tracks them automatically from your check-ins, and gives you an honest Bayesian verdict on whether they actually moved your numbers.
"50 members enrolled in the Neuronic trial getting 39% discount. You'd pay full price alone."
"I would have never heard of P-tau testing or Care Access without this group. And the daily tracking helped me see which interventions actually moved my numbers."
Watch John’s story →
Every APOE4-relevant trial on ClinicalTrials.gov, filtered to your profile, refreshed daily. Express interest in one tap and get a warm intro, not a cold application.
We partner with med-tech and pharma companies: you share anonymized outcomes data, they provide subsidized access to their innovations.
By purchasing as a collective, we negotiate significant group discounts on everything from diagnostics, to supplements or devices.
Now in the Phoenix app
Most APOE4 carriers find a trial after the cohort is full. Phoenix flips that — every relevant study from ClinicalTrials.gov, checked against your profile every morning, with reasons spelled out for every match.
New APOE4 trials checked against your profile every morning, before recruitment fills.
Age, genotype, sex, country, and your eligibility profile — Phoenix checks it all.
Express interest in a click. Sponsors meet a real, ready-to-recruit APOE4 carrier.
Population-based cohort study tracking biomarker progression in elderly carriers — designed to detect AD years before clinical onset.
Prevention trial evaluating subcutaneous gantenerumab in cognitively normal APOE4 homozygotes aged 55–75.
Sourced from ClinicalTrials.gov (NIH/NLM registry) and refreshed every 24 hours.
“Self-compassion has its own snowball effect. When you say, ‘well, I had fun, tomorrow’s another day’ — that’s the most loving thing you can do for yourself. And it keeps you going.”— Deb Blum, APOE4/4 · Health Coach, Scottsdale, ArizonaWatch Deb’s story →
Each month, Phoenix AI analyzes your goals, health data, and journey stage to match you with 2-4 APOE4 carriers — creating a support system built around what you're working on right now.
Cardiovascular fitness, biomarker optimization, cognitive performance, etc.
E4/E4 vs E3/E4 carriers have different optimization strategies
Match with members at similar stages or who've achieved what you're targeting
Communication style, age range, lifestyle factors
Phoenix AI will build your pod around the goals you set each month.
APOE4 4/4 • 57 • Seattle
Goal: Optimize cardiovascular fitness
Achievement: VO2 max 38 → 52 in 8 months
APOE4 3/4 • 42 • Austin
Goal: Reduce inflammation markers
Achievement: ApoB 115 → 70 in 6 months
APOE4 4/4 • 67 • Boston
Goal: Sleep & recovery optimization
Achievement: Sleep quality +60% in 3 months
Research shows that peer accountability increases adherence by 95% compared to going it alone. When people like you—with the same genetic risk—are counting on you, you show up differently.
"The people in the community — they're motivated, engaged, curious, smart, capable. They're vulnerable too. They share when something hasn't worked out. They're human."
Hear more member stories →
Not just personalized — validated across 565+ APOE4 carriers. 89% of members improve at least one biomarker within 6 months.
Your protocol targets 27 biomarkers with APOE4-specific ranges — validated by 89% of members improving within 6 months.
Source: Member outcomes, 6-month cohort
Pod members stay on track through shared accountability, protocol sharing, and real-time support.
Source: Pod accountability data
Simple daily check-ins or AI-validated experiments — your choice. 81% report better well-being within 3 months.
Source: Member surveys, 3 months
Focus on what works and what fits your life. Our members see measurable results fast.
Source: Member surveys
"One thing I really like about Phoenix is how we're so much looking at the evidence. The community lets me talk through decisions without burning out the people closest to me."
Watch Gertrude’s story →
Exclusive Partners & Perks
Members save an estimated $1,600+/year through our curated partners. 20% off the omega-3 that actually reaches APOE4 brains. 20% off a brain-age clock built by an MIT neuroscientist. Hundreds off medical devices that let you see if your protocols work. Every partner hand-picked by Kevin. Because we only partner with companies that actually move the needle for APOE4 carriers.
See all partner savingsFor members who want a team and a voice
Phoenix works because of the framework, the data, and the community. Phoenix Pro adds the people — and a seat at the table. Monthly 1:1s with longevity experts who carry APOE4 themselves. Clinical trial priority plus a say in which trials we pursue next. And direct input into how Phoenix evolves — because the people whose data is on the line should help decide what gets built.
$8,999/year · 60-day money-back guarantee · Limited Pro seats each quarter
Take our 3-minute assessment. We'll show you where to start based on your unique APOE4 profile.
60-day money-back guarantee — because your APOE4 protocol should be based on your data.
“Your information is legitimate. There’s a lot out there — people have all kinds of weird websites. Your stuff is real.”
Watch Donna’s story →