NCT07549074 · NOT YET RECRUITING
Multicomponent Intervention to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment
This trial is testing a combination of brain-training exercises and healthy lifestyle education in older adults who already have mild cognitive impairment (MCI). Researchers want to know whether these activities, used together or separately, help maintain or improve thinking and memory skills. Phase NA means this is a practical intervention study — not testing a drug, but evaluating a structured program. It is a blinded, randomized controlled trial with 200 participants across four groups.
Eligibility criteria
The inclusion criteria: 1. age 60 years or older; 2. diagnosis of MCI or mild neurocognitive disorder according to the Diagnostic and Statistical Manual of Mental Disorder (Fifth edition, Text Revision) (American Psychiatric Association, 2022); Participants who are not diagnosed with MCI will undergo a screening assessment by a research assistant using both the Montreal Cognitive Assessment (MoCA) (Chinese version) with a total score of 19 to 21 represents MCI. (Yeung et al., 2014); 3. awareness of memory loss with memory complaints; 4. member of collaborating elderly centre; 5. able to participate independently in group activities; and 6. fluent in Cantonese. The exclusion criteria: Those diagnosed with dementia, unable to participate independently in group activities, exhibiting disruptive behavior and/or severely impaired by physical disabilities (e.g. a severe hearing problem) are excluded.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-23