NCT07497867 · RECRUITING
Long-term Prospective Study of Korean CADASIL Patients
This is a 10-year observational study tracking 500 Korean patients who have CADASIL, a rare inherited condition that damages blood vessels in the brain and leads to strokes and dementia. Researchers will follow symptoms, brain scans, memory tests, and genetic data over time to understand how the disease progresses. There is no drug or intervention being tested — this is a natural history study, meaning it watches and records rather than treats.
You may qualify if
- Age ≥ 19 years
- CADASIL suspected or confirmed by genetic testing (NOTCH3 mutation)
- Able to provide written informed consent (participant or legally authorized representative)
You're excluded if
- Contraindication to MRI (claustrophobia, metal implants, pacemaker)
- Acute ischemic or hemorrhagic stroke within 180 days prior to enrollment
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-13