NCT07485725 · NOT YET RECRUITING

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 3

This trial is testing an AI-powered digital assistant designed to help older adults manage everyday health tasks — things like finding support services, handling medical bills, and navigating Medicare.gov. It is a behavioral study, not a drug trial, focused on whether this kind of decision-support technology is useful and practical for people with mild cognitive impairment. Phase NA means this is not a traditional drug-development phase — it is more of a technology development and usability study.

Eligibility criteria

Inclusion Criteria:
Project 1:
* 65+ years of age
* Able to read English at the 6th grade level
* Have 20/60 vision with or without correction.
Project 2:
* 62+ years of age
* Able to read English at the 6th grade level
* Have 20/60 vision with or without correction.
* Clinical diagnosis of mild cognitive impairment (MCI)
* Subjective cognitive complaints
* Evidence by clinical evaluation
* Clinical Dementia Rating Global scale of 0.5-2.0
* Probable MCI
* Montreal Cognitive Assessment (MoCA) score of 18-26
* No major Instrumental activities of daily living (IADL) impairments
* Geriatric Depression Scale of 4 or Below
* No diagnosis of dementia
Project 3:
* 60+ years of age
* Able to read English at the 6th grade level
* Have 20/60 vision with or without correction.
* MoCA score of 23 or lower
Exclusion Criteria:
All Projects:
* Blind or have visual impairments that limit their ability to view the technology.
* Deaf or have hearing impairments that limit their ability to answer telephone queries.
* Have a life-limiting/terminal illness
* Severe motor impairment (e.g., severe tremors or debilitating arthritis in their hands) that impairs ability to speak or use dominant hand
Project 1:
- Chronic neck pain/injury that might make the headset uncomfortable
Project 2:
- Cognitive impairment (MOCA ≤ 25)

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-03-20

View full record on ClinicalTrials.gov

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