NCT07454824 · RECRUITING
e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most
This trial tests whether sending educational materials through a patient portal, followed by a pharmacist-led conversation, can help older adults with MCI or dementia safely reduce medications that may be risky for the brain. These are called CNS potentially inappropriate medications. It is a pilot study, meaning researchers are gathering early data on whether the approach is practical and promising, not yet proving it works at scale.
Eligibility criteria
Inclusion Criteria: * Patients: Age ≥65, with a diagnosis of MCI or dementia based on ICD-10 codes and ≥1 active CNS-PIM, who are active patient portal users. Care partners: * Family or other companions >21 years who regularly help the patient with managing medications. Exclusion Criteria: * As the trial will be based in primary care, individuals residing in long term care facilities or enrolled in hospice will be excluded.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-06-16