NCT07441122 · NOT YET RECRUITING
Enhancing Attention in Elderly Using a Brain-Computer-Interface
This trial is testing whether mindfulness meditation and gentle electrical brain stimulation (delivered through a headset while performing a memory task) can strengthen attention-related brain signals in older adults, including those with mild cognitive impairment. A computer reads brainwaves in real time and adjusts the intervention on the fly. This is a Phase NA study, meaning it is exploratory research focused on whether the approach shows measurable brain effects, not a late-stage proven treatment.
Eligibility criteria
Inclusion Criteria: Younger adults: * Good general health. * Normal or corrected vision. * no history of neurological/psychiatric disease * ability to read and understand English * ability to understand information and ability to give a free and informed consent Older adults: * Normal or corrected vision. * Self-reports no current diagnosis of dementia. * Ability to provide written/electronic, informed consent. Exclusion Criteria: Younger Adults: * Neurological or psychiatric diseases that could be contraindicated for tACS (e.g., personal history of epilepsy/seizure brain damage, history of fainting, bipolar disorder, schizophrenia, current substance use disorder, etc.). * Medications that elevate seizure threshold (e.g., stimulant medication, high dose bupropion). * Factors hindering EEG acquisition and tACS delivery (e.g., skin infection, wounds, dermatitis, inability to access the scalp of the participant). Older Adults: * Neurological or psychiatric diseases that could be contraindicated for tACS (e.g., personal history of epilepsy/seizure brain damage, pacemakers, history of fainting, bipolar disorder, schizophrenia, current substance use disorder, etc.). * Medications that elevate seizure threshold (e.g., stimulant medication, high dose bupropion). * Factors hindering EEG acquisition and tACS delivery (e.g., skin infection, wounds, dermatitis, inability to access the scalp of the participant). * Diagnosis of dementia. * Do not have the capacity to provide informed consent.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-06-09