NCT07417891 · NOT YET RECRUITING
Ketogenic Diet to Reduce Osteoarthritis Pain in MCI
This trial is testing whether a ketogenic diet can reduce joint pain and improve physical function and cognition in adults who have both osteoarthritis and mild cognitive impairment. Researchers will measure symptoms and biological markers before and after the dietary program. This is a Phase NA trial, meaning it is a practical intervention study rather than a drug trial moving through standard approval phases. Details on duration and size are limited so far.
You may qualify if
- English speaking
- Diagnosis of major joint osteoarthritis
- Diagnosis of mild cognitive impairment
You're excluded if
- Diabetes that requires insulin
- Cancer requiring chemo- or radiation therapy in the last 2 years
- Cardiac event within 1 year
- Recent history of renal stones
- Diagnosis of fibromyalgia
- Already following a ketogenic diet
- Following a dietary pattern that does not allow for a ketogenic approach
- Unable to control one's diet
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-05-04