NCT07364019 · RECRUITING

The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia

This trial is testing an online educational program called Brain Health PRO, which teaches lifestyle changes aimed at reducing dementia risk. Over six months, participants work through the program at their own pace, fully online. Half start right away; the other half start six months later as a comparison group. This is a Phase NA study, meaning it is evaluating real-world effectiveness of a behavioral program, not a drug or medical device.

Eligibility criteria

Inclusion Criteria:
* Completion and documentation of the electronic Informed Consent Process (from the participant)
* Sufficient proficiency in English or French to undergo online assessments and participate in an online educational program.
* Technical ability to participate in an online educational program and remote assessments (i.e., regularly have access to a computer or tablet with an internet connection; have access to a desktop or laptop computer with an internet connection at least once every 6 months; ability to send and receive emails; ability to complete online assessments)
* Sufficient vision to participate in an online educational program and complete online cognitive testing
* Ages 50-80
* Classified as being at increased risk of dementia based on at least one of the following:
  * First-degree family history of dementia
  * Education level at or below high school (grade 12 or less)
  * Self-Reported: Hypertension, Hypercholesterolemia, Body Mass Index > 30 kg/m2 (derived from NIH Metric BMI Calculator), or Physical Inactivity (active is defined as engaging in a minimum of 20- 30 min of physical activity causing sweating and breathlessness, at least 2 times a week)
Exclusion Criteria:
* Individuals who have a clinical diagnosis of Dementia (based on self-report)
* Individuals who are currently participating in or have participated in a past study involving BHPro

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-05-19

View full record on ClinicalTrials.gov

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