NCT07347574 · NOT YET RECRUITING
NeuroCare Community Project: A Community Based Prospective Observational Study for Early Alzheimer's Detection in HK
This observational study in Hong Kong is tracking elderly adults over 2 to 3 years to see whether blood biomarkers can reliably detect Alzheimer's disease early, before or during mild cognitive impairment. Researchers will compare blood tests against MRI and PET scans to validate them as lower-cost screening tools. This is not a treatment trial — no intervention is given. It is a data-gathering study focused on Chinese populations, where this kind of longitudinal biomarker data is currently scarce.
You may qualify if
- Mentally capable of providing informed consent, with or without an informant present
- Willing and able to undergo blood draw and complete study related assessments; willing to be contacted for follow-up
You're excluded if
- Lacks capacity to consent even with an informant present
- Refuses or is unable to provide blood samples or complete essential assessments
- Currently enrolled in another clinical trial that could interfere with this study
- Known illness that prevents longitudinal follow up or uncontrolled medical illness such as neurodevelopmental disorder, neurodegenerative disease, epilepsy, central nervous system infection, neuroinflammatory diseases, brain tumor, cerebrovascular diseases, history of major psychiatric illness, history of major head injury with altered consciousness, sexually transmitted disease including HIV and syphilis, visual and auditory disability, history of alcohol dependence, substance use disorder, systemic autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, or malignancy.
- Active delirium or evidence of reversible/secondary causes of cognitive impairment (e.g., vitamin B12 deficiency, hypothyroidism) until treated/ stabilized
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-01-20