NCT07321821 · ACTIVE NOT RECRUITING

Fermented Garlic Lettuce Powder and Cognitive Function in Adults With Mild Cognitive Impairment

This trial is testing whether a fermented garlic lettuce powder supplement, taken daily for two months, improves cognitive function and psychological well-being in adults who already show signs of mild cognitive impairment. Participants are compared against a placebo group. This is a Phase NA trial, meaning it is a straightforward controlled study rather than a drug approval pathway, typically used for supplements and behavioral interventions.

You may qualify if

  • Adults aged 19 years or older with K-MoCA scores between 16 and 23.
  • Individuals with sufficient vision and hearing to participate in the study without difficulty.
  • Participants who are currently taking medications or receiving treatments that may affect cognition and are able to maintain the same dosage and regimen throughout the study period.
  • Individuals who voluntarily agree to participate in the study and provide written informed consent.

You're excluded if

  • Individuals who have undergone vascular-related surgery within the past 6 months or gastrointestinal surgery that may affect absorption of the study product (excluding simple appendectomy or hernia repair).
  • Individuals with a clinically significant history of hypersensitivity to medications or dietary supplements.
  • Individuals with a history of alcohol or drug abuse.
  • Individuals unable to communicate effectively.
  • Individuals who have participated in more than two dietary supplement studies or clinical trials within the current year, or within the past 6 months.
  • Individuals deemed unable to participate safely or effectively in the study by the investigator.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-01-12

View full record on ClinicalTrials.gov

All APOE4 clinical trials