NCT07214974 · Early Phase 1 · NOT YET RECRUITING
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
This early-phase trial is testing three things together: a wearable brain-computer interface device, experimental stem cell therapy, and structured wellness care for adults 55 and older who have mild cognitive impairment or early cognitive decline. It aims to measure whether these interventions slow cognitive decline compared to standard care. Early Phase 1 means this is very preliminary — safety and basic feasibility are still being established, and nothing here is proven or approved.
Eligibility criteria
Inclusion Criteria: Adults aged 55 years and older Residents of U.S. urban or suburban communities Able to provide informed consent Willing to participate in 3-year follow-up assessments Able to complete cognitive screening assessments Access to transportation for community-based appointments No prior formal diagnosis of dementia Exclusion Criteria: Adults under 55 years of age Current diagnosis of moderate to severe dementia Severe psychiatric disorders that would interfere with assessment validity Active substance abuse disorders Severe visual or hearing impairments that cannot be corrected and would prevent assessment completion Terminal illness with life expectancy less than 3 years Current participation in other cognitive intervention research studies Inability to attend follow-up assessments due to geographic relocation plans Significant neurological conditions (stroke, traumatic brain injury, Parkinson's disease) that could confound cognitive assessment Institutionalized individuals (nursing home residents)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-10