NCT07160959 · NOT YET RECRUITING
Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions
This trial is testing whether a home-based walking and strength training program can improve memory and thinking in people with advanced chronic kidney disease who already show early cognitive problems. Researchers will compare the exercise group to a standard-care group to measure changes in brain function. This is a Phase NA behavioral trial, meaning it is evaluating a structured lifestyle intervention rather than a drug.
You may qualify if
- CKD at KDOQI stage 4-5
- concomitant MCI (MOCA - MMSE (17 \< MoCA \< 26) or (16 \< MMSE \< 24)
You're excluded if
- Absolute contraindication to exercise training (e.g. unstable angina, major amputation, severe heart failure, etc.)
- Known life expectancy \< 6-month
- Uncorrected anemia (Hb \<9 g/dl)
- Non-provision of informed consent
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-09-08