NCT07051408 · ACTIVE NOT RECRUITING
Predictors Of Cognitive Decline Using Digital Devices
This study is testing whether people with memory concerns will actually use digital devices — a smartwatch, a sleep headband, and smartphone apps — in their daily lives, and whether the data collected can be combined with clinical records to build machine learning models that might one day predict dementia risk. It is not a treatment trial. It is an observational feasibility study, meaning researchers are checking whether this kind of data collection is even practical before doing anything larger.
You may qualify if
- Patients who present to the Essex Memory Clinic and their relatives or carers
- Capacity to provide written informed consent
- Sufficient proficiency in English to understand study documents and use the digital devices
- Own a compatible smartphone (Android 7.0 or higher / iOS 12.2 or higher). If participants own a smartphone which is not a compatible device (i.e. prior to Android 7.0 or iOS 12.2), a new handset will be provided to them, as long as they are willing to use this as their primary phone.
- Ability to use a smartphone and EDoN digital devices, either alone, or with appropriate support (carer, partner, family member, etc). Support would involve reminding participants to complete study tasks and to charge / wear devices.
- Able to connect to the internet using their smartphone at home. Note: In order to use the Dreem headband, participants will additionally require a home WiFi connection. However, participants without a WiFi connection will still be able to join the study and will not be asked to use the Dreem headband.
- For people with a diagnosis of dementia, a carer, partner or family member willing to support their participation in the study by reminding patients to complete study tasks and to charge/wear their devices
- For patients who do not have a record of neurocognitive and physical assessments outlined in section 4.5.3, they must be willing to undergo these additional assessments
- For the blood donation sub study only: consented to participate in the main CODEC II study.
- For the qualitative sub study only: able to use a phone or video-conferencing platform to participate in the interviews
- Aged 40+ years
You're excluded if
- Patients with active major psychiatric disorder which requires regular reviews by secondary care, for example schizophrenia, schizoaffective disorder or bipolar affective disorder
- Patients under end-of-life care
- Previous sensitivity or allergic skin reaction to latex, rubber or plastics
- Do not have a personal smartphone with internet access
- Participating in a clinical trial of an investigational medicinal product
- Not meeting all inclusion criteria
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-05-14