NCT07031167 · NOT YET RECRUITING
The COMFORTage Project at Ace Alzheimer Center Barcelona
This trial is testing whether a personalized digital training program combining cognitive and physical exercises can help slow memory and thinking decline in people with mild cognitive impairment or early Alzheimer's. Participants do weekly in-person sessions for one year using tablet and computer-based tools, then are followed for a second year. It is a Phase NA randomized trial — comparing the program against no intervention to see if it makes a measurable difference.
You may qualify if
- Age between 60 and 85 years.
- Diagnosis of MCI based on Petersen criteria with a CDR score of 0.5.
- Diagnosis of mild AD dementia according to National Institute on Aging-Alzheimer's Association (NIA-AA) criteria with a CDR score of 1.
- Proficiency in using digital tools such as mobile apps, tablets, or computers.
- Ability and willingness to attend regular in-person sessions at Ace Alzheimer Center Barcelona.
- Provided written informed consent after receiving a full explanation of the study.
You're excluded if
- History of traumatic brain injury.
- Diagnosis of severe depression.
- History of stroke or brain tumors.
- Presence of significant uncorrected visual or auditory impairments.
- Lack of access to a digital device or internet connection.
- Inability to participate in regular in-person sessions at the study site.
- Any medical condition that may confound cognitive assessment or limit participation.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-06-22