NCT06935578 · RECRUITING
RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)
This Italian registry study is building a national network to improve diagnosis of rare inherited and acquired cerebrovascular diseases — conditions like CADASIL, Fabry disease, and Moyamoya — that often go unrecognized as stroke causes. It is not a drug trial. Researchers are collecting clinical, genetic, and imaging data to better understand these conditions and close the gap between specialized northern Italian centers and underserved regions. Phase is unspecified because this is an observational registry, not an intervention study.
You may qualify if
- patients with a clinical, genetic and/or neuroradiological diagnosis of rCVD (CADASIL, Fabry's disease, COL4A1, Sneddon's syndrome or Moyamoya arteriopathy), who have had at least one brain MRI study;
You're excluded if
- na
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-02-24