NCT06838494 · NOT YET RECRUITING
Using Immersive Virtual Reality for Cognitive Therapy in Elderly with Mild Cognitive Impairment
This trial tests whether cognitive stimulation therapy delivered inside a virtual reality headset works better than standard cognitive stimulation therapy for older adults with mild cognitive impairment. Researchers will also track eye movements during VR sessions to see if that data predicts who responds best. This is a Phase NA feasibility and efficacy study — it is exploratory, not a proven or approved treatment.
You may qualify if
- elderly aged 60 years or above,
- a diagnosis of MCI made by a psychiatrist, or a score of 16-21 out of 30 in the Hong Kong Brief Cognitive Test (HKBC, 31), with upper and lower cutoff scores for MCI as suggested by the test. HKBC has been validated in Hong Kong with satisfactory sensitivity (0.88) and specificity ((0.81) in differentiating subjects with MCI and healthy individuals,
- ability to speak and comprehend Cantonese,
- normal or corrected-to-normal binocular vision and hearing,
- absence of physical illness/disability to prevent them from IVR-CST participation, 6, compatible with IVR exposure in the 10-minute IVR trial without major signs of cybersickness, based on the symptoms given in the Simulator Sickness Questionnaire
You're excluded if
- concurrent participation in other clinical therapy trials,
- incompatibility with IVR exposure such as complaints of nausea, headache, or other severe discomforts during trial use,
- a diagnosis of dementia or other psychiatric/neurological diseases such as depression, stroke, brain trauma, Parkinson's disease
- hearing/visual/upper limb impairments that hinder CST/IVR-CST participation,
- prior CST treatment,
- Use of medication for MCI/dementia, e.g., aducanumab
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-02-20