NCT06792877 · RECRUITING
Mindfulness for Cognition in Early-stage Alzheimer's Disease
This trial is testing whether a mindfulness meditation program can improve memory, thinking, brain function, and quality of life in older adults — some with mild cognitive impairment and some without. One group takes the mindfulness class right away; the other waits, then takes it. This is a Phase NA behavioral trial, meaning it is studying a non-drug intervention and gathering evidence on whether it works, not testing a drug for approval.
You may qualify if
- Healthy older adults will show cognitive performance within 1.0 SD for age \& education adjusted norms on a neuropsychological test battery
- Mild cognitive impairment (MCI) participants will show performance on delayed recall or one more or more other cognitive domains worse than 1.5 SD for age \& education adjusted norms, an MMSE score between 25-30, and a MoCA score between 20-30.
You're excluded if
- Participants without a computer, smart phone and internet access will be excluded
- If they cannot understand the informed consent form or have moderate dementia.
- Mood disorders (e.g., PTSD, depression, anxiety) or alcohol and drug use that either interferes with day-to-day life or required hospitalization within the past 5 years
- Cerebrovascular disease
- Any medical condition whose severity could significantly impair cognition (e.g., stroke, frontotermporal dementia, Parkinson's disease) are exclusionary
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-01-27