NCT06791720 · NOT YET RECRUITING
Effects of Music-with-Movement on Cognitive and Physical Performance of People With Potentially Reversible Cognitive Frailty: a Randomised Controlled Trial
This trial is testing whether combining music with movement — a simultaneous mental and physical workout — improves thinking, physical ability, and wellbeing in older adults who have both mild cognitive impairment and physical frailty at the same time. Participants either join structured music-movement sessions or weekly social gatherings over 16 weeks, with follow-up at 28 weeks. This is a Phase NA behavioral trial, meaning it is evaluating a non-drug program rather than a medication.
You may qualify if
- Aged 60 and above;
- Community-dwelling, as defined by living at home and not having stayed in a long-term care facility in the last 12 months as reported by the participants;
- Able to walk independently or with a stick;
- A cutoff value of = 0 in the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) indicates the participants' physical stability;
- A cutoff score of = 0.5 in the Clinical Dementia Rating indicates participants with Mild Cognitive Impairment (MCI);
- A cutoff score of ≥1 on the FRAIL Scale indicates participants with physical frailty;
You're excluded if
- Is suffering from any critical medical or psychiatric illness;
- Has an uncorrectable visual and/or hearing impairment that hinders the participation;
- Is having the MCI or physical frailty only;
- Is participating in other trials;
- Chronic use of corticosteroids, immunosuppressive drugs, androgen-, estrogen-, or progestin-containing compounds
- Taking psychotropic, antiarrhythmic, or hypnotic medications
- Advised by healthcare professionals (e.g., physicians or physiotherapists) not to participate in moderate-to-vigorous exercises.
- Older adults with special conditions or increased risk of injuries that require substantial adjustment in exercise regime, including those with COPD, renal disease, cancer, etc.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-02-13