NCT06670820 · NOT YET RECRUITING
iTBS in MCI and Mild AD
This trial tests whether a non-invasive brain stimulation technique called intermittent theta burst stimulation (iTBS) — a focused pattern of magnetic pulses delivered to the forehead — can improve thinking and memory in people with mild cognitive impairment or early Alzheimer's disease. It also measures changes in BDNF, a protein tied to brain health. This is a Phase NA trial, meaning it is exploratory research rather than a late-stage efficacy study.
You may qualify if
- Clinical diagnosis of MCI (overall Clinical Dementia Rating of 0.5)
- Clinical diagnosis of mild Alzheimer's Disease (overall Clinical Dementia Rating of 0.5 or 1)
You're excluded if
- History of stroke
- History of uncontrol seizure
- History of significant head trauma followed by persistent neurologic deficit or known structural brain abnormality
- Mental illness
- Drug abuse
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-11-01