NCT06650969 · RECRUITING
China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)
This is an observational study based in China tracking people with Type 2 diabetes to better understand how and why cognitive problems develop over time, from earliest warning signs through mild impairment to dementia. Researchers are building a detailed database combining brain imaging, biological samples, and cognitive testing. No new drug or device is being tested here — this is a data-gathering effort to improve future diagnosis and treatment. The phase is unspecified, consistent with a registry or cohort study rather than a clinical trial.
You may qualify if
- Age ≥45 years;
- Type 2 diabetes diagnosed according to the American Diabetes Association criteria;
- Willingness and ability to complete systematic neuropsychological tests;
- Understanding of the research procedures and methods, potential benefits and risks of the trial, and sign written informed consent.
You're excluded if
- Fewer than 6 years of education;
- Left-handedness;
- Dementia;
- Acute metabolic complications such as diabetic ketoacidosis, hyperglycaemic hyperosmolar state and hypoglycaemic coma within the previous 3 months;
- History or presence of neurological or psychiatric disorders;
- Presence of hypothyroidism;
- History of malignancy, or severe kidney or liver dysfunction.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-10-21