NCT06389812 · ACTIVE NOT RECRUITING
Dual-task Exercise in People With Cognitive Impairment
This trial tests whether a single 30-minute session of dual-task exercise — resistance bands combined with eye movement training — can immediately boost brain chemistry (BDNF), cerebral blood flow, thinking ability, and mobility in people with mild to moderate cognitive impairment. It is a Phase NA study, meaning it is exploratory research measuring immediate biological and cognitive responses rather than a long-term treatment trial. Details on site and enrollment status are limited.
Eligibility criteria
Inclusion Criteria: * Age \>65 (PwD or cognitively impaired older adults) (ICD-10) * People with and without cognitive impairment (MMSE score 13-30) * Subjects must be able to exercise at a moderate intensity level (see exclusion criteria) * Subject must be willing and able to provide a blood sample Exclusion Criteria: * • Subjects with other neurological disease (stroke, Parkinson's, or multiple sclerosis) * Significant current orthopaedic (fractures, hemiplegia, pain, arthritis etc.), cardiovascular and pulmonary conditions (arrhythmias, uncontrolled hypertension, acute bronchitis, cardiac insufficiency etc.) that would limit the ability to perform cardio-respiratory fitness assessment, tasks or exercise * Psychiatric conditions (depression, anxiety disorder, etc.) and a history of severe psychiatric disorders (schizoaffective/bipolar disorders, or schizophrenia) * Severe vision/hearing impairments that cannot be corrected with aids * Unable to comprehend questionnaire material study procedures
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-04-29