NCT06372535 · NOT YET RECRUITING
Effects of Tai Chi Chuan With Different Doses on Cognitive Function in Elderly Patients With Mild Cognitive Impairment
This trial is testing whether Tai Chi Chuan helps cognitive function in older adults with mild cognitive impairment, and whether the amount of Tai Chi practiced makes a difference. Nine different exercise doses are being compared. It is a Phase NA trial, meaning it is a practical behavioral study rather than a drug trial moving through standard approval phases. It is designed to find the most effective exercise volume, not to approve a product.
You may qualify if
- Presence of mild cognitive impairment, not demented;
- Age ≥ 60 years old;
- Informed consent and voluntary participation.
You're excluded if
- Geriatric Depression Scale score ≥ 9 points
- Cognitive impairment caused by other reasons, taking drugs, poisoning, etc;
- Suffer from severe musculoskeletal system diseases and other contraindications to exercise and are not suitable for Tai Chi training, such as those who suffer from stroke, Parkinson's disease, and have a history of lower limb arthritis, hip and knee joint replacement, etc;
- Patients with severe heart, liver, kidney failure, malignant tumors, and other major diseases;
- Individuals with visual/auditory impairments, writing/reading impairments, illiteracy, etc. that affect training and evaluation;
- Individuals with uncontrolled hypertension (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg after medication);
- Participating in other experiments that influence this study;
- Engaged in regular exercise in the last three months (at least 3 times a week, at least 20 minutes of regular exercise each time.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-04-18