NCT06201533 · RECRUITING

Low-intensity Physical-cognitive Exercise and Cognitive Function

This trial tests whether a low-intensity exercise program that combines physical movement with cognitive tasks can improve brain function in older adults with mild cognitive impairment. Participants do the combined workout three times a week for three months, and researchers measure cognitive performance and biological markers in the blood. This is a Phase NA behavioral trial — it is studying whether the approach works, not a drug being reviewed for approval.

You may qualify if

  • meeting the criteria for MCI (or mNCD) based on the recent DSM-V criteria
  • comprehend instructions and able to comply with the study procedures
  • not taking any medications for their cognition and not planning to start medications during the study trial

You're excluded if

  • presence of medical condition(s) unsafe to exercise or affect cognition and mobility
  • presence of depressive symptoms
  • exercise regularly

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-02-19

View full record on ClinicalTrials.gov

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