NCT06083350 · ACTIVE NOT RECRUITING
Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment
This trial is testing whether a daily yeast beta-glucan supplement can improve thinking and memory in people who already have mild cognitive impairment. Researchers think it might work by changing the balance of gut bacteria. Half the participants get the real supplement, half get a plain starch capsule as a placebo, for six months. This is a Phase NA trial — a practical clinical study designed to test effectiveness, not yet a proven or approved treatment.
Eligibility criteria
Inclusion Criteria: * 1. Aged 50-80 years; * 2. Permanent residents of Shiyan City; * 3. Meet the diagnostic criteria of MCI: * 4. Willing to cooperate in completing questionnaire survey and clinical examination, and sign informed consent; * 5. Did not participate in other clinical trials in the past 3 months. Exclusion Criteria: * 1. Alcohol or drug abuse; * 2. Patients with neurological diseases that may cause cognitive dysfunction, including cerebrovascular diseases, stroke, brain tumors, Parkinson's disease, active epilepsy, etc.; * 3. History of severe head trauma; * 4. Severe sensory and perceptual impairment, unable to complete the cognitive function measurement; * 5. History of mental illness such as depression, mania, anxiety, or take psychiatric drugs; * 6. Serious heart, lung, liver, kidney dysfunction, malignant tumors, etc.; * 7. Suffering from autoimmune diseases; * 8. Trauma, spinal injury or any disease that may affect the motor function of the limb; * 9. Recent infectious diseases, acute gastrointestinal diseases; * 10. Take antibiotics, probiotics, prebiotics or biostime products within the last 1 month.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-05-14