NCT05909189 · RECRUITING
LEADing Dementia End-of-Life Planning Conversations
This trial is testing a web-based tool called LEAD that helps people in the early stages of Alzheimer's or mild cognitive impairment have end-of-life planning conversations with family and caregivers. It aims to help them document and share their wishes before cognitive decline makes that harder. This is a Phase NA study, meaning it is focused on refining and evaluating a practical tool, not testing a drug.
You may qualify if
- Care Recipient (CR) is age 50+
- CR Is interested in having conversations about and documenting wishes for future end-of-life care
- CR has noticed changes in memory or thinking skills indicative of preclinical or early stage of AD, OR
- CR has been diagnosed with mild cognitive impairment, Alzheimer's disease, or another type of dementia and in the preclinical or early stage
- Care Partner (CP) is age 18+
- CP is a Spouse/partner, family member, or close friend of CR
You're excluded if
- Has moderate to severe symptoms of dementia
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-09