NCT05886114 · RECRUITING
A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China
This trial is testing whether a structured program combining exercise, nutrition, cognitive training, social activities, and vascular risk management can slow cognitive decline in older adults already showing early warning signs. It enrolls 1,200 community residents in Zhejiang, China, over two years. This is a Phase NA randomized controlled trial, meaning it is evaluating real-world effectiveness of a behavioral program rather than a drug.
You may qualify if
- At risk of cognitive decline: cognitive performance at the mean level or slightly lower than expected for age with no dementia (AD8>=3 and/or 5-min MoCA >, \< 11)
- Free of physical disabilities that preclude participation in the study
- Willing to complete all study-related activities for 24 months
- Willing to be randomized to either lifestyle intervention group
You're excluded if
- Diagnosed dementia patients
- Diagnosed major depression or other neuropsychological diseases
- Malignant diseases
- Symptomatic cardiovascular disease
- Revascularization within one year
- Severe loss of vision, hearing or communicative ability
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2023-06-06