NCT05734378 · RECRUITING
Prognosis of Cerebral Small Vessel Disease
This is an observational study, not a drug trial. Researchers are following people already diagnosed with cerebral small vessel disease to track what happens over time. They want to understand how the type of disease and the way it first showed up affects long-term outcomes. No treatment is being tested. Because no phase is specified, this is a natural history study meant to improve how doctors predict risk.
You may qualify if
- Hypertensive deep perforator arteriolopathy (DPA), clinically symptomatic with either ICH, ischaemic stroke, cognitive impairment or severe radiological manifestation (Fazekas ≥II)
- Cerebral amyloid angiopathy (CAA according to modified Boston or Edinburgh criteria), clinically symptomatic with either ICH (including cSAH), amyloid spells, cognitive impairment or severe radiological manifestation (CMB≥2)
- Other SVD (i.e. CADASIL or other sporadic or genetic SVD)
You're excluded if
- Life expectancy of \<6 months due to not-SVD related causes (i.e. cancer)
- Patient is unlikely to attend follow-up visits
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2023-03-08