NCT05201534 · RECRUITING
Interventions in Mathematics and Cognitive Skills
This trial is studying how the brain responds to math tutoring in children ages 6 to 12, including kids with math learning disabilities. Researchers are comparing two educational approaches and using brain scans to understand what changes in the brain when children improve their number skills. This is a Phase NA study, meaning it is a behavioral and neuroscience investigation rather than a drug trial. Details on the specific interventions are limited so far.
You may qualify if
- Elementary school aged children starting from first grade (6-12 years old)
- IQ: Participants with a Full Scale IQ > 70 on the Wechsler Abbreviated Scle of Intelligence (WASI-II).
- Identification of Mathematical Learning Disabilities: Scores below the 35th percentile percentile on symbolic number processing test in Numeracy Screener and two or more Wechsler Individual Achievement Test (WIAT-IV) math subtests
- Identification of typically developing children: Scores at or above the 35th percentile percentile on symbolic number processing test in Numeracy Screener and all WIAT-IV math subtests
- Normal or corrected-to-normal vision and no hearing impairments
- Inclusion in MRI scan session: Right-handed
You're excluded if
- History of neurological or psychiatric disorder (i.e., schizophrenia, psychosis, depression, or attention deficit hyperactivity disorder.)
- History of trauma involving head injury
- Consistent psychiatric medications
- Exclusion from MRI scan session: No major contraindication for magnetic resonance imaging (MRI) - braces, metal implants, pacemakers, vascular stents, metallic ear tubes, consistent exposure to metal, claustrophobia)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-08-15