NCT04938349 · RECRUITING
Dual Task Perturbation Training for OAwMCI
This trial tests a specialized treadmill training program for older adults with mild cognitive impairment (MCI). A motorized treadmill delivers sudden balance disruptions while participants also perform a cognitive task at the same time. Researchers want to know if this combined challenge is safe and practical, and whether it improves balance, muscle responses, and thinking. This is a Phase NA pilot study — a small early-stage test of feasibility, not a proven treatment.
You may qualify if
- Age group: Older adults between the age group > 55 years old with MOCA less than 26 out of 30 will be classified as mild cognitive impairment and those above 26 out of 30 as cognitively intact older adults .
- Absence of any acute or chronic neurological (Stroke, Parkinson's disease, Alzheimer's disease), cardiopulmonary, musculoskeletal, or systemic diagnosis.
- No recent major surgery (\< 6 months) or hospitalization (\< 3 months)
- Not on any sedative drugs
- Can understand and communicate in English
- Ability to walk more than 10 meters without an assistive device
You're excluded if
- Participants will not proceed with the study if any of the following occurs at baseline measurement: 1) HR > 85% of age-predicted maximal heart rate (HRmax) (HRmax = 220 - age), 2) systolic blood pressure (SBP) > 165 mmHg and/or diastolic blood pressure (DBP) > 110 mmHg during resting), and/or 3) oxygen saturation (measured by pulse oximeter) during resting \< 90%.
- History of bone fracture or significant other systemic disease or surgery in the last six months
- Specific to MRI participants: Self-reported presence of a pacemaker, metal implants other than orthopedic implants, and/or Claustrophobia, cataract surgery (lens not compatible to the MRI confirmed by the MRI technician)
- Weighs > 220 lbs (Harness weight threshold)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-11-26