NCT04033510 · ACTIVE NOT RECRUITING
Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)
This study tests whether people with atrial fibrillation (an irregular heart rhythm) think and remember less clearly during an AF episode than when their heart is back in normal rhythm. Researchers use a tablet-based cognitive test battery to measure the difference. It is not a drug trial — it is an observational study tracking standard care. No phase is listed, meaning it is not a traditional drug-development trial.
You may qualify if
- Subjects who are patients at CSC or Penrose-St. Francis Health Services.
- Subjects actively in an episode of paroxysmal, or persistent AF (who are expected to receive treatment and converted back to normal rhythm (through antiarrhythmic drug therapy, direct current cardioversion, ablation or Maze/Minimally invasive Maze procedure).
- Subjects with a history of AF who have had >3 documented episodes of AF over the preceding 12 months and meet all other inclusion/exclusion criteria can pre-enroll. The cognition tests will be administered during the patient's next captured AF episode.
You're excluded if
- Patients who had coronary bypass surgery during their life time.
- Patients with a previously documented history of post-pump syndrome during their life time.
- Patients with presence of, or medical diagnosis of Transient Ischemic Attack (TIA) or Cerebral Vascular Accident (CVA).
- Patients with presence of, or medical diagnosis of cognitive impairment (dementia, multiple sclerosis, traumatic brain injury, etc.).
- Female patients who are pregnant or post-partum.
- Individuals unwilling or unable to take an anticoagulant.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-10-14