NCT07496918 · Phase 2 · RECRUITING
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
This trial tests whether flickering light and sound at 40 Hz (a specific brain-wave frequency) plus a tactile vibration device can produce measurable biological changes in the brain. Researchers at MIT will use EEG, MEG, MRI, and blood tests to look for those effects in cognitively healthy adults during a single one-day visit. It is a Phase 2 trial, meaning researchers are exploring whether the approach works and is safe, not a proven or approved treatment.
Eligibility criteria
Inclusion Criteria: * Have adequate visual and auditory acuity for visual and auditory stimulation to allow for neuropsychological testing. * Be able to comply with neuropsychological testing and other study procedures in opinion of site PI. Exclusion Criteria: Participants will be screened for the following exclusion criteria including if they * History of seizure or medical diagnosis of epilepsy. * Have MRI contraindications, such as presence of pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments, or foreign objects in the eyes, skin, or body. * Under the discretion of the site investigator, the site investigator feels the subject cannot complete sufficient key study procedures. Exceptions to these guidelines may be considered on a case-by-case basis at the discretion of the Project Director.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-27