NCT07424443 · ACTIVE NOT RECRUITING
Pilot Study of a Brain Health Program in Senior Centers
This pilot study is testing a behavioral program called My Healthy Brain, delivered at senior centers, for older adults who notice memory slipping but do not have dementia. It is not measuring whether the program prevents Alzheimer's — it is checking whether the program is feasible, acceptable, and runs as intended. This is a Phase NA pilot, meaning it is early-stage groundwork, not a test of effectiveness yet.
You may qualify if
- Aged ≥ 50
- Subjective cognitive decline (SCD; e.g., forgetting information, getting lost, and repeating oneself)
- Able to self-identify at least 1 modifiable lifestyle risk factors for dementia to change during the program (physically inactive, poor sleep, non-adherence to Mediterranean diet, alcohol use, tobacco use, socially isolated or lonely, mental inactivity)
- Absence of significant cognitive impairment (assessed using Short Blessed Test71 ≤ 9)
- Self-reported English proficiency/literacy
- Ability and willingness to participate and complete all study-related activities
You're excluded if
- Dementia or other neurodegenerative disease per patient self-report or disclosure
- Psychosis, uncontrolled schizophrenia or schizoaffective disorder, uncontrolled bipolar disorder, or uncontrolled substance dependence/abuse
- Active self-report of suicidal ideation / high risk of suicide
- Serious medical illness expected to worsen during the study
- Self-reported safety issues with initiating lifestyle change
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-06-15