NCT07409597 · NOT YET RECRUITING
Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease
This observational study is testing whether eye-tracking technology, combined with standard memory tests, can reveal how Huntington's disease affects autobiographical memory — the ability to recall personal past events and imagine future ones. Researchers will compare HD patients to healthy controls. This is a Phase NA study, meaning it is not a drug trial — it is research designed to better understand a cognitive problem, not to test a treatment.
Eligibility criteria
Inclusion criteria For patients: * Adults at inclusion * Huntington's disease diagnosed and confirmed by genetic analysis * Patients in the presymptomatic stage of HD with a motor UHDRS score ≤ 5 and patients in symptomatic stages 1-2 of HD with a motor UHDRS score > 5 and a CFT between 6 \< CFT ≤ 13 * Patients who have given their written informed consent or consent from a third party * Affiliated with or beneficiary of a social security system For healthy controls: Pre-inclusion criteria * Adults at inclusion * Individuals with no history of neurological disorders (interview and clinical examination) * Signature of informed consent to participate in the study * Affiliated with or beneficiary of a social security system * Matching in age (± 5 years), sex, and level of education with an HD patient included in the control group Inclusion criteria • MMSE ≥ 24/30
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-06