NCT07316413 · RECRUITING
Repetitive Transcranial Magnetic Stimulation in Frontotemporal Lobar Degeneration
This trial is testing repetitive transcranial magnetic stimulation, or rTMS, in people diagnosed with frontotemporal dementia or in healthy family members who may be at risk. Using a magnetic device held near the skull, researchers deliver brief pulses to stimulate brain activity. They want to know if it is safe, feasible, and whether it changes clinical or biological markers of the disease. This is a Phase NA trial, meaning it is exploratory rather than a standard efficacy-proving phase.
You may qualify if
- diagnosis of FTLD (bvFTD, avPPA, svPPA, CBS, or PSP)
- global CDR plus NACC FTLD ≤ 1
You're excluded if
- presence of cerebrovascular disease, hydrocephalus, intracranial masses identified by MRI, history of head trauma, serious medical conditions unrelated to FTLD, history of epilepsy, and presence of electronic (e.g., pacemaker) or metallic implants in the head.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-01-05