NCT07315984 · NOT YET RECRUITING
Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease
This study is testing whether wearable sensors and digital tools, such as smartphone assessments and pendant or wrist sensors, can accurately track symptoms in Huntington's Disease. It is an observational study, not a treatment trial, meaning no drug or intervention is being tested. Participants wear sensors and complete digital tasks over 12 months. The goal is to validate these tools as reliable ways to measure disease activity. Details beyond that are limited.
Eligibility criteria
Inclusion Criteria: * Male or female, aged 25-65 years * For HD participants: Genetically diagnosed with HD * Fluent in English (able to speak and read). * Ambulatory without the need for a walking aid. * Able to independently perform all study activities safely, as determined by the investigator. * Willing and able to provide informed consent and comply with all study procedures. For control participants: * Male or female, aged 25-65 years * Clinically assessed to be in good health, with no evidence of neurological disorders that could cause involuntary movements or gait disturbances Exclusion Criteria: * Diagnosis of juvenile-onset HD. * Individuals who are non-ambulatory. * Individuals with a neurological, medical, or psychiatric condition that, in the investigator's judgment, would interfere with safe participation in study activities. * Montreal Cognitive Assessment (MoCA) score of 18 or lower * Pregnant individuals, due to potential changes in gait and physical activity during pregnancy. * Cannot be enrolled into a blinded intervention trial at baseline.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-01-05