NCT07288736 · ACTIVE NOT RECRUITING
Aromatherapy Formulas for Sundowning and Sleep Quality in Patients With Dementia.
This trial is testing two different essential oil blends — one using rosemary and lemon in the morning paired with lavender and sweet orange in the afternoon, the other a broader calming blend — to see if aromatherapy can reduce agitation and improve sleep in people with dementia who experience sundowning. It is a Phase NA crossover study conducted in long-term care facilities in Taiwan, meaning it is exploratory in nature and not yet generating definitive proof.
You may qualify if
- Diagnosis of dementia by a specialist according to DSM-5 (any type) OR SPMSQ score \< 8.
- Manifesting sundown syndrome with a score ≥ 26 on the CMAI-C.
- Able to speak Mandarin or Taiwanese.
You're excluded if
- Clinical diagnosis of a psychiatric disorder (e.g., schizophrenia, bipolar disorder).
- Acute stage of illness within the past 2 weeks.
- Olfactory disorder or loss of smell (anosmia).
- Allergy to essential oil fragrances.
- Currently receiving aromatherapy.
- Respiratory disease (e.g., asthma, COPD).
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-01-08