NCT07205978 · ACTIVE NOT RECRUITING

Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis

This is not a clinical trial in the usual sense. It is a large-scale data analysis project called NUTPOOL that will pool raw data from many existing long-term diet studies around the world. Researchers want to understand whether eating nuts regularly is linked to lower risk of diseases like dementia, diabetes, heart disease, and cancer. No intervention is being tested on participants directly. Details on phase are unspecified because this is observational research, not a drug or treatment trial.

Eligibility criteria

Inclusion Criteria:
Prospective studies with:
* Dietary data (consumption of nuts, both overall and/or by type) from semiquantitative food frequency questionnaires
* Available data on at least two of the health outcomes of interest
* More than 1,000 adult participants (aged 18 and over)
* A minimum of five years of median follow-up
Exclusion Criteria:
* Prospective studies determining the consumption of nuts in combination with other food groups (e.g., seeds) or with other nut forms (e.g., butter or oil)
* Participants with:
* Missing data on age, sex, and nut consumption.
* Extreme energy intakes (\<600 or >3,500 kcal for women and \<800 or >4,200 kcal for men)
* The disease of interest at baseline

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-03-20

View full record on ClinicalTrials.gov

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