NCT07205003 · RECRUITING
Evaluation of the Link Between Carotid Arterial Wall Viscosity and Major Neurocognitive Disorders
This study uses ultrasound measurements of the carotid artery wall to see whether its stiffness and energy-dissipation properties differ between people with Alzheimer's disease, vascular dementia, and people with memory complaints but no dementia diagnosis. It is a diagnostic or observational study, not a drug trial, meaning no phase is assigned and nothing is being prescribed or treated. Details on sample size and timeline are limited.
You may qualify if
- Age over 70
- Memory consultation consultant (neurology or geriatrics)
- Brain MRI less than one year old or planned as part of the cognitive assessment performed.
- Patient diagnosed with Alzheimer's disease according to DSM-5 criteria or vascular dementia according to DSM-5 criteria, or presenting a memory complaint without evidence of a dementia-related condition.
- No objection from the patient or their caregiver.
- Patient covered by a health insurance plan
You're excluded if
- Known unilateral or bilateral carotid stenosis or history of carotid surgery
- Permanent CA/AF
- Patient presenting with confusion
- Known psychiatric illness (severe depression, psychosis, etc.)
- Non-vascular, non-Alzheimer's dementia (e.g., Lewy Body Dementia, Parkinsonian Dementia, Progressive Supranuclear Palsy)
- Refusal to participate
- MMS less than or equal to 10
- Contraindication to performing an MRI
- Any acute decompensated pathology
- Patient under guardianship or curatorship
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-05-22