NCT07204145 · NOT YET RECRUITING

Laser Acupuncture for Behavioral and Psychological Symptoms of Dementia

This trial is testing whether laser acupuncture — a non-invasive device that uses a low-level laser pen to stimulate traditional acupuncture points — can reduce behavioral and psychological symptoms in people already living with dementia, such as agitation, anxiety, or sleep problems. It compares real laser acupuncture against a sham version. This is a Phase N/A trial, meaning it is a practical effectiveness study rather than an early drug-safety test.

You may qualify if

  • Diagnosis of Dementia: Participants must have a clinical diagnosis of dementia, of any type or severity
  • Consent: Written informed consent provided by the participant's family or legal representative.

You're excluded if

  • Refusal to sign the informed consent form.
  • Unable to cooperate with the intervention procedure despite repeated attempts.
  • History of epilepsy.
  • End-stage liver disease.
  • End-stage renal disease requiring hemodialysis.
  • Presence of brain tumor or history of major brain surgery.
  • Acute cardiovascular or cerebrovascular events within the past 3 months (e.g., unstable angina, myocardial infarction, stroke).
  • Use of a cardiac pacemaker.
  • Currently receiving acupuncture or traditional Chinese medicine treatment.
  • Presence of acute illness.
  • Abnormal blood pressure or fever.
  • Presence of malignant tumor.
  • Pregnancy.
  • Presence of unusual physical abnormalities or sensory nerve disorders.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2025-10-02

View full record on ClinicalTrials.gov

All APOE4 clinical trials