NCT07118137 · RECRUITING

Memory Deterioration in Alzheimer Disease

This study is observational, not a drug trial. Researchers are using high-powered 7 Tesla MRI, EEG brain scans, blood draws, stool samples, and cognitive tests to better understand how memory breaks down in people who already have Alzheimer's disease or mild cognitive impairment. The goal is to learn more about the biology of memory loss, not to test a treatment. The phase is unspecified, consistent with a research observation study.

You may qualify if

  • Confirmed diagnosis based on current ICD criteria for AD or MCI .
  • >55years.
  • Norwegian native speaker
  • Lives at home and not in a health institution

You're excluded if

  • Patients with severe cognitive impairment that prevents assessment with the selected modalities (planned cut-off: CDR > 2).
  • Presence of brain tumors.
  • History of traumatic brain injury.
  • History of cranial surgery.
  • Contraindications to the selected imaging modalities (e.g., 7T MRI or EEG).
  • Diagnosis of other neurodegenerative diseases such as Parkinson's disease or ALS. 7T MRI contraindications:
  • Large tattoos close to the head region, permanent makeup or unremoveable piercings
  • Certain models of pacemakers (if pacemaker implantet, MRI physicist at 7T-lab will be conferred)
  • Implantet metal in body (clips, stents, prothesis, skrews, plates, teeth etc.)

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2025-08-12

View full record on ClinicalTrials.gov

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