NCT07109999 · RECRUITING

Biomarker-based Alzheimer's Disease Cohort Study (BASIC)

This is an observational study, not a treatment trial. Researchers in China are enrolling people who already have confirmed Alzheimer's-related biomarkers, such as amyloid detected on a PET scan or spinal fluid test, and following them over time. The goal is to track how their disease progresses, identify what risk factors speed things up, and build a prediction model. No drug or intervention is involved.

You may qualify if

  • (1) Patients aged 40 years or older;
  • (2) Visiting Xuanwu Hospital, Capital Medical University;
  • (3) Meeting the core clinical diagnostic criteria for Alzheimer's disease (AD) - related mild cognitive impairment or probable AD according to the NIA-AA (2011);
  • (4) Amyloid positivity confirmed by amyloid PET or cerebrospinal fluid biomarker tests;
  • (5) Providing informed consent.

You're excluded if

  • (1) Individuals who are unable to complete the assessment due to severe psychological or physiological disorders.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2025-08-07

View full record on ClinicalTrials.gov

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