NCT07033468 · RECRUITING
The Feasibility and the Efficacy of the Full-immersive Virtual Reality Cognitive Training in Patients With Mild or Moderate Dementia
This trial is testing a fully immersive virtual reality program designed to train and stimulate cognition in people who already have mild to moderate dementia. Participants wear a VR headset and complete leisure-based cognitive activities across 15 sessions over five weeks. Researchers are measuring changes in cognitive function, daily living skills, and quality of life. This is a Phase NA feasibility and efficacy study — early-stage work to see whether the approach is practical and shows promise, not a proven treatment.
You may qualify if
- Age over 55 years;
- Diagnosed with mild or moderate dementia (primarily degenerative dementia) by a consulting physician or based on past medical records;
- A score of at least 11 but no more than 23 on the Mini-Mental State Examination (MMSE);
- Has at least one family member or a regularly contacted friend (with the person's mobile number and contact at least once a week);
- Able to walk independently and complete the Timed Up \& Go (TUG) test;
- Able to follow instructions with or without the assistance of a guardian or therapist;
- If the assessment indicates moderate dementia, further evaluation will be conducted to determine whether the participant has sufficient capacity to provide informed consent. If their capacity is found to be impaired, the study will be explained to their legal representative
You're excluded if
- Dementia with Lewy Bodies and other dementia types resulting from specific causes, such as Huntington's Disease, substance addiction, central nervous system infections, nutritional deficiencies, and metabolic disorders.
- Severe health conditions that may hinder safe participation, such as respiratory distress, severe cardiovascular disease, or brain tumors.
- A psychiatric diagnosis of psychosis within the past six months.
- Diagnosis of Korsakoff syndrome.
- History of substance addiction.
- Severe hearing impairment or color blindness.
- History of severe vertigo or epilepsy.
- Concurrent participation in other studies that may affect cognitive function
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-06-24