NCT06877312 · RECRUITING
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
This trial is testing six different types of non-invasive brain stimulation — mild electrical currents delivered through the scalp — combined with cognitive exercises, to see which frequency or pattern works best for people with dementia. Participants cycle through each stimulation type in random order, with rest periods in between. This is a Phase NA longitudinal observational and comparative study, meaning researchers are tracking effects over time rather than seeking regulatory approval.
You may qualify if
- ability to read, write and speak English fluently
- MoCA score between 5 and 24
You're excluded if
- Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder.
- Having a history of epileptic seizures or epilepsy
- Inability to adequately communicate in English
- Impaired vision or hearing severe enough to impair performance in cognitive tests
- Current substance abuse disorder
- Currently participating in another therapeutic study for dementia
- Plan to change the medication during any treatment period (5 weeks including the pre-post assessments)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-12-04