NCT06754254 · ACTIVE NOT RECRUITING

Blood Biomarkers from Internal Jugular Vein for the Diagnosis of Alzheimer's Disease

This observational study is testing whether blood drawn from the internal jugular vein in the neck gives more accurate Alzheimer's biomarker readings than blood drawn from the standard arm vein. Researchers think brain-draining blood may carry stronger signals of disease. No phase is specified because this is not a drug or treatment trial — it is a diagnostic accuracy study, meaning no intervention is being given.

You may qualify if

  • age: 40-90 years old (including 40 and 90 years);
  • patients with cognitive complaints or concerns;
  • Willing and able to comply with all aspect of the protocol and provide written informed consent. If a subject lacks capacity to consent in the investigator's opinion, the subject's assent should be obtained, if required in accordance with local laws, regulations and customs, plus the written informed consent of a legal representative should be obtained (capacity to consent and definition of legal representative should be determined in accordance with applicable local laws and regulations).

You're excluded if

  • Severe medical conditions which are not stably and could affect the subject's safety;
  • Presence of contraindications for PET examination, cerebrospinal fluid or blood collection;
  • Unwilling and refuse to participate in this study.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2024-12-31

View full record on ClinicalTrials.gov

All APOE4 clinical trials