NCT06731049 · RECRUITING
Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease
This trial compares two walking programs for people already diagnosed with Alzheimer's disease: standard treadmill walking versus treadmill walking combined with simultaneous cognitive challenges, like counting or naming things while moving. Researchers want to know which approach better improves walking, balance, thinking, and daily functioning. This is a Phase NA trial, meaning it is a direct comparison study rather than an early safety or efficacy phase. Details on size and location are limited so far.
You may qualify if
- Diagnosis of Alzheimer's disease according to the NINCDS-ADRDA criteria by a neurologist,
- In the early or middle stages of the disease according to the Clinical Dementia Rating Scale (CDR),
- Receiving medical treatment for Alzheimer's disease (e.g., cholinesterase inhibitors or memantine) for at least the past month,
- Able to walk at least 400 meters in the 6-Minute Walk Test, indicating functional mobility,
- Able to read and understand instructions given in Turkish.
You're excluded if
- Having Lewy body dementia, frontotemporal dementia, or other types of dementia
- Participating in a structured exercise program within the 6 months prior to starting the study
- Having pulmonary, neurological, musculoskeletal, or rheumatological diseases that hinder walking
- Having an unstable medical condition (e.g., uncontrolled diabetes or hypertension, deep vein thrombosis, etc.)
- Having visual or auditory impairments that make communication difficult
- Having behavioral problems that make participation in exercise difficult
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-31