NCT06559254 · NOT YET RECRUITING
TDCS as Augmentation Therapy to Cognitive Training in Mild Dementia
This trial tests whether adding a mild brain stimulation technique called tDCS (transcranial direct current stimulation) to standard cognitive training helps people with mild dementia think more clearly. Participants get 10 sessions over two weeks, and half receive real stimulation while half receive a sham version. It is a Phase NA (feasibility or pilot-level) study — meaning researchers are still working out whether the combined approach is worth pursuing further, not a proven treatment.
You may qualify if
- 65 years of age or above
- Right-handedness Chinese as defined by Edinburgh handedness inventory
- Cantonese speaking
- Fulfil the criteria of Major neurocognitive disorder, as defined by the 5 th Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM- 5)
- Clinical Dementia Rating Global score = 1
You're excluded if
- Active diagnosis of mood disorder or psychosis
- Alcohol or substance dependence
- Initiation or change in dose of cognitive enhancer within 6 months prior to the onset of the study 14
- Poor physical condition and mobility
- Having regular cognitive training (as defined by at least three 1-hour weekly structured and standardized cognitive training in recent 3 months) 15
- Receiving tDCS within 2 months prior to the onset of study 16
- Significant communication or visual impairment
- Having metal implant in area above upper back, or having metal crown or metal brace, or pacemaker
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-08-19