NCT06528951 · ACTIVE NOT RECRUITING
Impact of Resistance Training Volume on Cognitive Function and Physical Performance in Cognitively Impaired Individuals
This trial tests whether doing more resistance training (lifting weights at 15%, 30%, or 45% higher volumes) improves cognitive function and physical performance in people already diagnosed with cognitive impairment. Researchers will also track inflammation, blood sugar, and other health markers. This is a Phase NA trial, meaning it is a straightforward interventional study rather than a formal drug development phase — testing a structured exercise protocol, not a medication.
You may qualify if
- Men or women aged ≥ 50 years old, diagnosed with cognitive impairment (mild, moderate, or severe) through the Dementia Rating Scale-2.
- SPPB score ≥ 3.
- Willingness to participate in training programs and collaborate with the research team.
- Able to provide informed consent (oral or written).
You're excluded if
- Severe comorbidity that negatively influences participation in the training program.
- Surgeries or fractures in the last 6 months.
- Bedridden or hospitalized individuals.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-07-30