NCT06442852 · RECRUITING

Study on the Relationship Between Peripheral Blood miRNA and Risk and Severity of Alzheimer's Disease

This study is looking at tiny molecules in the blood called microRNAs to see whether their levels differ between people with Alzheimer's and healthy volunteers, and whether those levels track with how severe the disease is. It is an observational study, not a treatment trial — no drug or therapy is being tested. The goal is to find possible early blood-based signals for Alzheimer's. Details on phase are not provided.

Eligibility criteria

Inclusion Criteria:
Alzheimer's disease patients:
* Meet the diagnostic criteria of NINCDS-ADRDA for AD
* Clinical Dementia Scale (CDR) score ≥0.5
Healthy volunteers:
* No complaints or symptoms of cognitive impairment
* MMSE score is higher than the threshold value
Exclusion Criteria:
Alzheimer's disease patients:
* Dementia or cognitive impairment due to other diseases
* Combined with delirium
* A history of drug abuse
* Severe deafness, aphasia and other impact scale score
Healthy volunteers:
* had an organic brain lesion
* Suffering from other major physical diseases: such as severe immune diseases

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2024-06-04

View full record on ClinicalTrials.gov

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