NCT06411561 · RECRUITING
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
This trial tests whether combining sleep improvement strategies with cognitive training helps older adults avoid mental decline after a stay in the ICU. Researchers will compare different combinations of behavioral programs, including sleep support, cognitive exercises, and activity coaching, to see which best protects thinking skills. It is a Phase NA study, meaning this is a practical intervention trial rather than a drug study, focused on real-world feasibility and effectiveness.
You may qualify if
- Age greater than or equal to 60 years old
- Current hospitalization at University of Washington Medical Center or Harborview Medical Center
- Intensive care unit (ICU) length of stay greater than 24 hours
- Recovery from critical care status to acute care status, and/or discharge out of ICU
- Fluent in English or Spanish
- Functional independence on activities of daily living prior to hospitalization (Katz Index = 6)
You're excluded if
- Documented history or suspicion of Alzheimer's disease or dementia, or current prescription of anti-dementia medication
- Documented history of bipolar disorder or schizophrenia
- Documented acute stroke or traumatic brain injury
- Severe vision impairment
- Severe hearing impairment
- Severe paralysis or dominant arm paresis
- Transfer from skilled nursing care facility or inpatient rehabilitation facility
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-07-20