NCT06304129 · NOT YET RECRUITING
Diagnostic Performance of Plasma Biomarkers of Alzheimer's Disease Compared With CSF Markers
This study tests whether blood draws can match the accuracy of spinal fluid tests for detecting Alzheimer's-related changes in the brain. Researchers will compare blood levels of proteins like amyloid and tau against the standard lumbar puncture results in patients already being evaluated for Alzheimer's at a French hospital. This is a diagnostic accuracy study, not a drug trial — it is trying to validate a less invasive test, not treat anything.
You may qualify if
- Man or woman aged 18 or over
- Person affiliated to a social security scheme or beneficiary of such a scheme
- Person who has received full information on the organization of the research and has signed an informed consent form
- Person whose care requires a lumbar puncture to measure markers of Alzheimer's disease
You're excluded if
- Adult subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
- An adult unable to give consent
- Persons deprived of their liberty by judicial or administrative decision
- Persons under psychiatric care under articles L. 3212-1 and L. 3213-1.
- Pregnant, parturient or breast-feeding women
- Persons staying in a health or social establishment for purposes other than research.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-03-12